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?:abstract
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Fifty-eight percent of the total infections in Italy of COVID-19 were found in northern Italy, in particular, Lombardy From February 21, 2020, to March 23, 2020, 20 patients with a fracture and a diagnosis of COVID-19 were hospitalized Demographic data, COVID-19 symptoms, laboratory and radiographic examinations, and treatment methods were recorded At 1-month follow-up, patients were assessed with the SF-36 score This case series includes 20 patients (16 women and 4 men), with an average age of 82 35 years (range 59-95) Eleven patients (55%) had a femur fracture Fourteen patients (70%) had 3 or more comorbidities or previous pathologies Three patients with severe comorbidities died during the hospitalization Thirteen patients (65%) had fever, 18 patients (90%) asthenia, and 17 patients (85%) dyspnea All patients (100%) were given antibiotic therapy, whereas 16 patients (80%) underwent hydroxychloroquine therapy and 8 (40%) were treated with corticosteroids Eighteen patients (90%) underwent antithromboembolic prophylaxis Eighteen patients (90%) had lymphopenia All 20 patients (100%) required noninvasive mechanical ventilation High D-dimer and polymerase chain reaction values were found in all patients (100%), whereas lactate dehydrogenase was increased in 18 patients (90%) Patients with fractures, especially in the lower limbs, frequently require hospitalization, making these patients more subjected to the risk of COVID-19 infection COVID-19 infection therefore does not seem to influence the fracture pattern in the elderly population but can lead to health deterioration with increased mortality The typical symptoms of COVID-19 disease have not changed when associated with a fracture or trauma Laboratory data are in line with what is reported in recent studies, whereas a more invasive assisted ventilation is associated with a poor prognosis Finally, analyzing the data obtained from the SF-36 score, significantly lower values emerged when compared with those reported in the literature
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