PropertyValue
?:abstract
  • We studied plasma antibody responses of 35 patients about 1 month after SARS-CoV-2 infection. Titers of antibodies binding to the viral nucleocapsid and spike proteins were significantly higher in patients with severe disease. Likewise, mean antibody neutralization titers against SARS-CoV-2 pseudovirus and live virus were higher in the sicker patients, by ∼5-fold and ∼7-fold, respectively. These findings have important implications for those pursuing plasma therapy, isolation of neutralizing monoclonal antibodies, and determinants of immunity.
?:creator
?:doi
  • 10.1080/22221751.2020.1823890
?:doi
?:journal
  • Emerging_microbes_&_infections
?:license
  • cc-by
?:pdf_json_files
  • document_parses/pdf_json/c60f19c7184f3d8ec5c467615e82a588b6a3ad82.json
?:pmcid
?:pmid
?:pmid
  • 32930052.0
?:publication_isRelatedTo_Disease
?:sha_id
?:source
  • Medline; PMC
?:title
  • SARS-CoV-2 neutralizing antibody responses are more robust in patients with severe disease
?:type
?:year
  • 2020-09-25

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