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Many survivors from acute respiratory distress syndrome (ARDS) associated with coronavirus disease 2019 (COVID-19) suffer from persistent dyspnea and fatigue long after resolution of the active infection. In a cohort of 25 consecutive COVID-19 ARDS survivors admitted to an inpatient rehabilitation hospital (76% male), 80% of them had at least one sonographic abnormality of diaphragm muscle structure or function. Specifically, when compared to established normative data, 76% had impaired contractility (reduced thickening ratio), and 20% patients had atrophy (reduced muscle thickness). These findings support neuromuscular respiratory dysfunction as a highly prevalent underlying cause for prolonged functional impairments after hospitalization for COVID-19.
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?:doi
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10.1101/2020.12.10.20244509
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document_parses/pdf_json/abd8db5b992663ed82e0fd254170397573d413c5.json
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?:title
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Short of Breath for the Long Haul: Diaphragm Muscle Dysfunction in Survivors of Severe COVID-19 as Determined by Neuromuscular Ultrasound
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