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Increased morbidity and mortality from SARS‐CoV‐2 coronavirus disease (COVID‐19) in people with obesity has illuminated the intersection of obesity with impaired responses to infections. While data is being rapidly generated on mechanisms by which COVID‐19 impacts health, there is a critical need to better understand the pulmonary, vascular, metabolic, and immunologic aspects that drive the increased risk for complications from COVID‐19 in people with obesity. In this review, we provide a broad overview of the intersection between COVID‐19 and physiology of obesity to highlight potential mechanisms by which COVID‐19 disease severity is increased by obesity, and to identify areas for future investigation towards developing tailored therapy for people with obesity who develop COVID‐19.
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Pathways to Severe COVID‐19 for People with Obesity
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