PropertyValue
?:abstract
  • The inflammatory response to severe acute respiratory syndrome-related coronavirus 2 infection has a direct impact on the clinical outcomes of coronavirus disease 2019 patients. Of the many innate immune pathways that are engaged by severe acute respiratory syndrome-related coronavirus 2, we highlight the importance of the inflammasome pathway. We discuss available pharmaceutical agents that target a critical component of inflammasome activation, signaling leading to cellular pyroptosis, and the downstream cytokines as a promising target for the treatment of severe coronavirus disease 2019-associated diseases.
?:creator
?:doi
  • 10.4049/jimmunol.2000513
?:doi
?:journal
  • Journal_of_immunology
?:license
  • unk
?:pmid
?:pmid
  • 32493814
?:publication_isRelatedTo_Disease
?:source
  • Medline
?:title
  • Inflammasomes and Pyroptosis as Therapeutic Targets for COVID-19.
?:type
?:year
  • 2020-06-03

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