PropertyValue
?:abstract
  • Envelope glycoproteins of many viruses are heavily glycosylated Among other functions, virus glycans can mediate interactions with host receptors and contribute to internalization and virus dissemination The C-type lectin receptor DC-SIGN, which is expressed by cells of the innate immune system, can act as an entry receptor for pathogens, including pandemic viruses such as SARS-CoV-2, ebola, and HIV In the context of the recent SARS-CoV-2 pandemic, this mechanism has been linked to severe cases of COVID-19 Inhibition of the interaction between
is ?:annotates of
?:creator
?:license
  • unk
?:publication_isRelatedTo_Disease
is ?:relation_isRelatedTo_publication of
?:source
  • WHO
?:title
  • Poly-L-lysine Glycoconjugates Inhibit DC-SIGN-mediated Attachment of Pandemic Viruses (preprint)
?:type
?:who_covidence_id
  • #2315
?:year
  • 2020

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