|
?:abstract
|
-
Reports of the incidence of acute kidney injury (AKI) in patients with COVID-19 have varied greatly from 0.5% to as high as 39%, with onset generally within 7 days from time of admission1. The nature of the kidney insult is acute tubular necrosis, immune cell infiltration or rhabdomyolysis as demonstrated in autopsy reports2 , 3. Moreover, infection with COVID-19 has been associated with coagulation abnormalities4, as well as complement-mediated generalized thrombotic microvascular injury5. These patients have been found to have high D-dimer, fibrin degradation product and fibrinogen values, an elevated INR, normal PTT and normal platelet counts. Renal artery thrombosis is a rare condition, the most common cause of which is atrial fibrillation. However, bilateral completely occlusive renal artery thrombosis is even rarer. We present a case of a patient with COVID-19 on systemic anticoagulation who presented with a serum creatinine of 6.04mg/dL requiring the initiation of kidney replacement therapy and was found to have bilateral renal artery thrombosis.
-
Reports of the incidence of acute kidney injury in patients with coronavirus disease 2019 (COVID-19) have varied greatly from 0 5% to as high as 39%, with onset generally within 7 days from time of admission The nature of the kidney insult is acute tubular necrosis, immune cell infiltration, or rhabdomyolysis, as demonstrated in autopsy reports Moreover, infection with COVID-19 has been associated with coagulation abnormalities, as well as complement-mediated generalized thrombotic microvascular injury These patients have been found to have high D-dimer, fibrin degradation product, and fibrinogen values, an elevated international normalized ratio, normal partial thromboplastin time, and normal platelet count values Renal artery thrombosis is a rare condition, the most common cause of which is atrial fibrillation However, bilateral completely occlusive renal artery thrombosis is even rarer We present a case of a patient with COVID-19 on systemic anticoagulation therapy who presented with a serum creatinine level of 6 04 mg/dL requiring the initiation of kidney replacement therapy and was found to have bilateral renal artery thrombosis
|
![[This page as RDF]](https://research.tib.eu/covid-19/static/rdf-icon.gif){kind=icon}