PropertyValue
?:abstract
  • Eleven compounds were isolated from methanol extract taken from Moringa oleifera seeds, including two previously unknown and nine known compounds. These compounds were authenticated as a carbamate, three phenylglycosides, four phenol glycosides, two nucleosides, and one flavonoid. Their chemical structures were elucidated using 1 D/2D nuclear magnetic resonance and high resolution-MS. Antivirus activity analyses revealed that Moringa A, glucomoringin, and Vitexin possessed strong inhibitory effects against the H1N1 virus, having IC50 values in the range of IC50 = 0.26 ± 0.03, 0.98 ± 0.17, and 3.42 ± 0.37 µg/mL, respectively. Furthermore, these three compounds could decrease the levels of TNF-α, IL-6, and IL-1ß, which occur in hosts because of H1N1 infections.
is ?:annotates of
?:creator
?:journal
  • Nat_Prod_Res
?:license
  • unk
?:publication_isRelatedTo_Disease
?:source
  • WHO
?:title
  • Isolation and identification of two new compounds from the seeds of Moringa oleifera and their antiviral and anti-inflammatory activities
?:type
?:who_covidence_id
  • #948585
?:year
  • 2020

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