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A 66-year-old male with a history of long-standing ulcerative colitis, managed with azathioprine and sulfasalazine, underwent a flexible sigmoidoscopy for a flare up of his symptoms. Endoscopy showed essentially normal mucosa (Mayo Score 0) but a fibro-epithelial polyp was observed at the ano-rectal junction and biopsied. No synchronous lesions, nor further polyps were detected on completion of the pancolonscopy. Histology from the biopsy showed high-grade dysplasia (HGD) with some features which raised the possibility of deeper invasion.
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Colorectal_disease_:_the_official_journal_of_the_Association_of_Coloproctology_of_Great_Britain_and_Ireland
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Scarless, entirely laparoscopic panproctocolectomy and extra-sphincteric dissection with perineal extraction of the specimen for cancer of the anorectal junction - Video Vignette.
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