PropertyValue
?:abstract
  • False negatives from nasopharyngeal swabs (NPS) using reverse transcriptase PCR (RT-PCR) in SARS-CoV-2 are high. Exhaled breath condensate (EBC) contains lower respiratory droplets that may improve detection. We performed EBC RT-PCR for SARS-CoV-2 genes (E, S, N, ORF1ab) on NPS-positive (n=16) and NPS-negative/clinically positive COVID-19 patients (n=15) using two commercial assays. EBC detected SARS-CoV-2 in 93.5% (29/31) using the four genes. Pre-SARS-CoV-2 era controls (n=14) were negative. EBC was positive in NPS negative/clinically positive patients in 66.6% (10/15) using the identical E and S (E/S) gene assay used for NPS, 73.3% (11/15) using the N/ORF1ab assay and 14/15 (93.3%) combined.
is ?:annotates of
?:creator
?:doi
  • 10.1136/thoraxjnl-2020-215705
?:doi
?:journal
  • Thorax
?:license
  • no-cc
?:pdf_json_files
  • document_parses/pdf_json/fad9149c09c97d4b43a1247bfde3af8b90c3ff51.json
?:pmc_json_files
  • document_parses/pmc_json/PMC7590263.xml.json
?:pmcid
?:pmid
?:pmid
  • 33097604.0
?:publication_isRelatedTo_Disease
?:sha_id
?:source
  • Medline; PMC
?:title
  • Use of exhaled breath condensate (EBC) in the diagnosis of SARS-COV-2 (COVID-19)
?:type
?:year
  • 2020-10-23

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