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  • Enzima que catalisa a oxidação do ácido araquidônico para dar 5-hidroperoxiaraquidonato (5-HPETE) que é convertido rapidamente pela peroxidase a 5-hidroxi-6,8,11,14-eicosatetraenoato (5-HETE). Os 5-hidroperóxidos são formados preferencialmente nos leucócitos.
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