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  • A human early embryonic event in which in any given cell one of a female\'s two X chromosomes becomes inactivated and converted into a Barr body. After inactivation has occurred, all descendants of that cell have the same inactivated X chromosome. Thus, X-inactivation creates cell clones with differing effective gene content. An organism whose cells vary in effective gene content and hence in the expression of a trait, is called a genetic mosaic.
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