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  • A procedure to limit bias by preventing subjects and/ or study personnel from identifying which treatments or procedures are administered, or from learning the results of tests and measures undertaken as part of a clinical investigation. NOTE: Masking, while often used synonymously with blinding, usually denotes concealing the specific study intervention used. [After ICH E6 (R2) Glossary, 1.10]. The term masking is often preferred to blinding in the field of ophthalmology. [from AMA Manual of Style]. See also double-blind study, single-blind study, triple-blind study. Contrast with open-label and/or unblinded study.
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