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  • Contrast media used to enhance the differences in signal intensity emitted from tissues during magnetic resonance-based imaging procedures. Magnetic resonance imaging contrast agents typically consist of paramagnetic (e.g., gadolinium-based, manganese-based) or superparamagnetic (e.g., iron oxide-based, iron platinum-based) particles that influence the magnetic resonance signals generated by surrounding tissues. Magnetic resonance imaging contrast agents may be administered intravenously, orally, or injected intra-articularly and may be designed to distribute non-specifically within the extracellular space of the body or specifically within certain target tissues (e.g., liver) or the intravascular space (i.e., blood pool).
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