C0242640_NCI_CDISC | Knowledge4COVID-19

Property	Value
?:definition	Simultaneous resistance to a spectrum of unrelated drugs following exposure to a single agent. Mechanisms involve expression of multidrug efflux pumps (p-glycoprotein), altered glutathione metabolism, decreased topoisomerase II activity, and changes in various cellular proteins.
?:hasCUIAnnotation	<https://research.tib.eu/covid-19/entity/C0242640>
?:hasGeneratedBy	<https://research.tib.eu/covid-19/SourceName/NCI_CDISC>
?:type	<https://research.tib.eu/covid-19/vocab/AnnotationDefinition>

Metadata

Anon_0

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Anon_0

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