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  • A malignant epithelial tumor arising from the ovary. It is characterized by an admixture of two or more of the five major cell types: serous, mucinous, endometrioid, clear, and Brenner/transitional. The second or second and third cell types must comprise alone or together at least 10% of the tumor epithelium, or, in the case of a mixed Brenner-mucinous cystic tumor, both components should be macroscopically visible. The least differentiated component determines the tumor grade (WHO, 2003). Check for \'https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C40090\' active clinical trials using this agent. (\'http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C40090\' NCI Thesaurus)
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