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  • A formulation in which liposomes are loaded with the cytokine interleukin-2 (IL-2). By activating cytotoxic T lymphocytes, such as lymphokine-activated killer cells, and increasing levels of the cytotoxic cytokines interferon-gamma (IFN-gamma) and transforming growth factor-beta (TGF-beta), IL-2 may exhibit antitumoral activity. Liposomal formulations of IL-2 may promote entry of the cytokine into target tumor cells and may be used as an immunoadjuvant in cancer vaccine therapy. Check for \'https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C2373\' active clinical trials using this agent. (\'http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C2373\' NCI Thesaurus)
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