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  • Electrical stimulators designed to induce sweating by the transdermal introduction of water-soluble electrolytic substances (e.g., pilocarpine) into the sweat glands using electric stimulus (iontophoresis). These stimulators typically consist of a direct-current generator and two electrodes connected to the generator by cords. After the stimulus is applied, the area where the positive electrode was located is cleaned with a sponge, and a filter pad or gauze covered with a chlorine-free, thermoplastic, self-sealing film is placed for about one hour to collect sweat. The pad is removed and weighed to determine if enough sweat was collected and sent to the clinical laboratory to analyze the chloride and/or sodium concentration. Transdermal iontophoresis sweat induction stimulators are used for diagnosis of cystic fibrosis in infants. Points-of-care analyzers combining the stimulator with the chemical analyzer are also available.
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