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  • Radio-frequency (RF) therapy systems designed for tissue coagulation necrosis at temperatures above 60 degrees C and/or tissue water vaporization above 100 degrees C (i.e., thermal ablation), usually at frequencies below 500 kHz. The mechanism for ablation at radio frequency occurs by heating due to tissue electrical resistance when electric current flows through them. These systems typically consist of a RF generator, a delivery cable, an applicator or catheter, and two electrodes. The active electrode, including temperature sensors, is placed on the tissue volume to be ablated using an applicator or catheter, and a large-area neutral electrode that reduces current density to avoid tissue heating is placed on the body surface. Some systems include needlelike electrodes (applicators) that are introduced into the organ to increase the volume of the treated tissue.
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