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  • Stage IV includes: IVA (T4a, N0, M0); (T4a, N1, M0); (T1, N2, M0); (T2, N2, M0); (T3, N2, M0); (T4a, N2, M0); IVB (T4b, Any N, M0); IVC (Any T, Any N, M1). T4a: Tumor invades the larynx, deep/extrinsic muscle of tongue, medial pterygoid, hard palate, or mandible. T4b: Tumor invades lateral pterygoid muscle, pterygoid plates lateral nasopharynx, or skull base or encases carotid artery. M1: Distant Metastasis. (AJCC 6th ed.) Check for \'https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C9218\' active clinical trials using this agent. (\'http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C9218\' NCI Thesaurus)
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