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  • Interleukin 2 (IL-2) is a potent cytokine that can lead to cellular activation and proliferation. IL-2 receptors are found on activated B-cells, LPS treated monocytes, and many T-cells. The receptor is formed from three chains, alpha (CD25), beta (CD122), and gamma (CD132). Primary signaling is through the JAK/Stat pathway and MAPKs. (This definition may be outdated - see the DesignNote.)
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