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A mouse monoclonal antibody (MoAb) with binding specificity for the human melanoma-associated cell surface marker p97. Hybridomas of mouse myeloma cells and mouse spleen cells immunized with human melanoma cell were produced, of which one secreted MoAb 8.2. MoAb 8.2 is a monoclonal IgG1 antibody that recognizes an epitope near the amino-terminal portion of p97. This agent is used for detection and binding to p97 antigen expressed on the cell surface of melanoma cells.
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