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  • A cyanopyrrolidine-based, orally bioavailable inhibitor of dipeptidyl peptidase 4 (DPP-4), with hypoglycemic activity. Vildagliptin\'s cyano moiety undergoes hydrolysis and this inactive metabolite is excreted mainly via the urine. Check for \'https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/C66653\' active clinical trials using this agent. (\'http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C66653\' NCI Thesaurus)
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