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  • Human HMOX1 wild-type allele is located within 22q12 and is approximately 13 kb in length. This allele, which encodes heme oxygenase 1 protein, plays a role in the conversion of heme to bilirubin and carbon monoxide. Certain allelic variants of the HMOX1 gene are associated with heme oxygenase 1 deficiency.
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