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  • Human ETV4 wild-type allele is located in the vicinity of 17q21 and is approximately 18 kb in length. This allele, which encodes ETS translocation variant 4 protein, plays a role in the activation of transcription by RNA polymerase II. Ewing sarcoma is linked to a chromosomal translocation t(17;22)(q12;q12) of this gene with the EWSR1 gene.
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