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  • Intense stimulation or persistent injury can cause plasticity of the central nociceptive circuits, synaptic plasticity and increased neuronal responsiveness in central pain pathways after painful insults is known as central sensitisation.
  • Intense stimulation or persistent injury can cause plasticity of the central nociceptive circuits, synaptic plasticity and increased neuronal responsiveness in central pain pathways after painful insults is known as central sensitization.
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