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  • Human CREB3L2 wild-type allele is located in the vicinity of 7q34 and is approximately 127 kb in length. This allele, which encodes cyclic AMP-responsive element-binding protein 3-like protein 2, plays a role in transcription that occurs in response to endoplasmic reticulum stress. A translocation t(7;16)(q32-34;p11) involving the FUS gene and CREB3L2 gene is associated with low-grade fibromyxoid sarcoma.
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