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Molecular assay reagents intended to identify mutations in the Harvey rat sarcoma viral oncogene homologue (HRAS) gene, located at chromosome 11p15.5, an oncogene that encodes for a protein involved in cell division. Mutations at this locus have been identified in patients with solid tumor cancers, including bladder cancer, invasive breast cancer, and differentiated liposarcoma; they are also associated with Costello syndrome.
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