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  • Molecular assay reagents designed for nucleic acid (e.g., DNA, RNA) amplification (i.e., replication). Samples are obtained from body fluid specimens and follow a repetitive process that increases the target nucleic acid copy number in each cycle. These reagents may be applied directly to DNA samples; however, RNA samples usually require preprocessing through a reverse transcription procedure. Reagents that can perform the replication either at constant temperature or through a thermal cycle are available. Nucleic acid replication reagents are used in clinical laboratories to generate large amounts of nucleic acid from a previously purified nucleic acid sample; the amplified sample is usually used for subsequent diagnostic or research.
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