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  • Molecular assay reagents intended for use in identifying exchanges (i.e., translocations)between chromosome 11 band q13 and chromosome 14 band q32, usually involving genes BCL-1 and IGH, respectively. This translocation is present mainly in patients with B-cell chronic lymphocytic leukemia (B-CLL), but it is also associated with other types of leukemia and multiple myeloma. Its detection may be used as a tumor marker.
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