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  • Molecular assay reagents intended for use in identifying exchanges (i.e., translocations) between chromosome 8 band q24 and chromosome 22 band q11, usually involving gene C-MYC on chromosome 8 juxtaposed with gene IGL at the immunoglobulin locus on chromosome 22. This translocation is characteristic of most patients with Burkitt\'s cell leukemia or Burkitt\'s lymphoma; other translocations involving the MYC locus and associated with Burkitt\'s lymphoma include t(8:14)(q24:q32) and t(2;8)(p12;q24). Its detection may be used as a tumor marker.
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