?:definition
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Molecular assay reagents intended for use in identifying exchanges (i.e., translocations) between chromosome 1 band p23 and chromosome 5 band q35, usually involving genes ALK and NPM1, respectively. This translocation is present in more than half the cases of anaplasic large-cell lymphoma (ALCL), a high-grade non-Hodgkin\'s lymphoma (NHL). Its detection may be used as a tumor marker.
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