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  • Clinical chemistry reagents intended to perform qualitative and/or quantitative analyses on a body fluid sample (e.g., whole blood, erythrocyte hemolysates) to determine the riboflavin (vitamin B2) status by measuring the enzyme glutathione reductase; this enzyme is typically measured indirectly (i.e., measuring the flavin adenine dinucleotide-dependent activity of the enzyme glutathione reductase). Decreased levels of vitamin B2 are characterized by the presence of sore throat, hyperemia, stomatitis, and edema of the oral and pharyngeal membranes; deficiency of riboflavin may also cause seborrheic dermatitis and some types of anemias.
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