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  • Immunoassay reagents intended to perform qualitative and/or quantitative analyses on a body fluid sample (e.g., serum) to determine Scleroderma-70 ([Scl-70], DNA topoisomerase I) antibodies. Circulating Scl-70 antibodies are present in some autoimmune connective-tissue diseases, particularly in scleroderma and progressive systemic sclerosis.
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