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  • Immunoassay reagents intended to perform qualitative and/or quantitative analyses on a body fluid sample (e.g., urine, bile, feces) to determine coproporphyrin, a porphyrin derivative. Coproporphyrin is moderately water soluble, thus it is excreted both in feces and in urine. High levels of coproporphyrin are found in toxic (acquired) porphyrias caused by one or more of a group of toxic agents (e.g., chronic ethanol exposure, lead, mercury, arsenic). Some dietary products, diseases (e.g., malignancies), and hereditary deficiencies (i.e., inherited porphyrias) may also cause abnormal coproporphyrin levels.
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