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Immunoassay reagents intended to perform qualitative and/or quantitative analyses on a body fluid sample (typically urine), to determine phenol (also known as carbolic acid) and/or one or more of a group of phenol-derivated compounds with the generic name of phenols characterized by a hydroxyl group directly attached to an aromatic ring. These products are usually metabolized in the liver and excreted in the urine. Reagents used to determine phenol/phenol compounds (e.g., o-, m-, p-cresol) concentration in urine are used to establish the degree of intoxication with phenol, cresol, and benzene and/or other hydrocarbons (e.g., toluene), frequently as the result of occupational exposure. It may also occur by accidental or intentional ingestion of phenol, creosol, or other related product. Phenol itself is considered a specific indicator of exposure to benzene.
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