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  • Immunoassay reagents intended to perform quantitative analyses on a body fluid sample (typically whole blood) to measure levels of tacrolimus (a macrolide isolated from the culture broth of a strain of Streptomyces tsukubaensis that has strong immunosuppressive activity in vivo and prevents the activation of T-lymphocytes in response to antigenic or mitogenic stimulation in vitro) in the sample. Reagents for measuring levels of tacrolimus (also known as FK 506) in the blood are used to monitor the drug levels in patients undergoing treatment to determine the adequacy of drug treatment or to diagnose a drug overdose or drug-related toxicity.
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