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  • Molecular assay reagents intended to identify mutations in the neuroblastoma RAS viral (v-ras) oncogene homologue (NRAS) gene, located at chromosome 1p13.2, which encodes for a membrane-linked protein that moves between the Golgi apparatus and the plasma membrane. The protein is a small GTPase. Mutations at this locus have been identified in patients with juvenile myleomonocytic leukemia (JMML), colorectal cancer, thyroid cancer, and follicular cancer.
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