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  • Molecular assay reagents intended for use in identifying stable and irreversible exchanges (i.e., translocations) between chromosomes 14 and 18, usually involving the exchange of the BCL2 gene with the joining region of the immunoglobin heavy chain of chromosome 14. The detection of these translocations may be used as a tumor marker. The translocation is present in most patients with follicular lymphomas and in some patients with acute lymphoblastic leukemia.
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