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  • Immunoassay reagents intended to perform qualitative and/or quantitative analyses on a body fluid sample (e.g., serum) to determine antibodies against cytoplasmic constituents of neutrophil granulocytes (i.e., antineutrophil cytoplasmic antibodies [ANCA]), such as proteinase 3 (PR3-ANCA), myeloperoxidase (MPO-ANCA), lactoferrin (LF-ANCA), and azurocidin. Increased circulating levels of ANCA are mostly associated with autoimmune systemic necrotizing vasculitis.
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