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Immunoassay reagents intended to perform qualitative and/or quantitative analyses on a body fluid sample (typically serum) to determine barbiturates, central nervous system neuronal activity suppressor drugs with little therapeutic use (e.g., sedative, hypnotic). Barbiturates (e.g., phenobarbital) have largely been replaced by benzodiazepines for sedative and hypnotic purposes. Reagents for determination of barbiturates are used in tests intended to monitor drug levels in patients as a result of either an induced therapeutic coma (anesthetic doses) or to diagnose and manage barbiturate intoxication caused by intentional or, less frequently, accidental ingestion.
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