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Immunoassay reagents intended to perform qualitative and/or quantitative analyses in tissue preparations to determine a cellular regulatory protein that binds estrogenic hormones (i.e., cytoplasmic estrogen receptors). These receptors are especially found in estrogen sensitive tissues (e.g., breast and uterus tissues). The assays are performed in surgically removed samples, and determination of the level of estrogen receptors is used as a marker of the response to endocrine therapy in diseases such as breast carcinoma.
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