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Immunoassay reagents intended to perform qualitative and/or quantitative analyses of a sample of body fluids (e.g., blood) to determine either one or more in the group of glycoproteins that are normally attached to mast cells (i.e., Immunoglobulin E) or the vasoactive amines (e.g., histamines) that are released by mast cells when an antigen (allergen) cross-links two attached IgE molecules; the presence of specific Immunoglobulin G subtypes may also be tested. These reagents are mostly used to characterize a patient\'s abnormal hypersensitivity to substances that are ordinarily harmless (allergens). Some reagents may be used to determine allergy mediators (e.g., leukotrienes, tryptase).
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