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Immunoassay reagents intended to perform qualitative and/or quantitative analyses of body fluids to measure levels associated with the total complement activity. These proteins are synthesized by the liver and are normally present in the blood as functionally inactive molecules. The values are usually expressed as hemolytic complement units per milliliter (known as CH50), representing the reciprocal of the dilution of serum required to lyse 50% of a standard preparation of erythrocytes previously coated with erythrocyte antibodies. This test is typically used for screening purposes; abnormal serum levels of complement components may be due to either inherited or acquired diseases.
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