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  • Immunoassay reagents intended to perform qualitative and/or quantitative analyses of body fluids (e.g., plasma, cervicovaginal exudates) to determine fibronectin, an adhesive glycoprotein that circulates in plasma and is present in many cell surfaces. Fibronectin is related to the aggregation of platelets. Fibronectin levels are decreased in hepatocellular diseases; low levels in plasma of chronic diabetic patients are associated with hyperglycemia complications. The presence of cervicovaginal fetal fibronectin in pregnant women is associated with an increased risk of preterm delivery. The presence of the oncofetal isoform of fibronectin from neoplastic tissues is a marker for angiogenesis, such as in intracranial meningiomas.
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