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  • Serology reagents intended to detect antibodies to hyaluronidase (i.e., Antihyaluronidase, [AHT]) produced by Streptococcus group A (typically Streptococcus pyogenes), a spherical bacterium of the family Streptococcaceae. S. pyogenes is one of the most important bacterial human pathogens, causing a wide range of suppurative diseases (e.g., pharyngitis, otitis media, sinusitis, endocarditis) and nonsuppurative sequelae (e.g., acute rheumatic fever). AHT antibodies are associated with some autoimmune diseases, including rheumatoid arthritis and osteoarthritis.
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