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  • Clinical chemistry reagents intended to perform qualitative and/or quantitative chemical analysis of body fluids (typically urine) to measure the total level of porphyrin. Analysis may include a profile of porphyrin components (e.g., uroporphyrin, coproporphyrin). Measurement of the total level of porphyrins is used in the diagnosis and management of one of a group of metabolic disorders, either inherited or acquired, usually known as porphyrias; measurement of the porphyrin-level profile in urine is used to characterize several specific diseases, such as porphyria cutanea tarda, that are associated with the presence of isocoproporphyrin. Some specific porphyrin analyses in whole blood are performed for screening purposes, such as zinc protoporphyrin for iron-deficiency anemia and free erythrocyteporphyrin determination for lead poisoning.
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