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  • Molecular assay reagents intended to identify deletions or duplications of the adenomatous polyposis coli (APC) gene, located at chromosome 5q21-q22, which encodes the adenomatous polyposis coli protein. Genetic variants at this locus have been associated with familial adenomatous polyposis 1, hepatocellular carcinoma, hereditary desmoid disease, carcinoma of the colon, and neoplasm of the stomach.
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