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  • Instruments designed for simultaneous determination of (1) the relative amount of oxygenated and deoxygenated hemoglobin (O2Hb and HHb, respectively) displaying the results as percent saturation of hemoglobin in arterial blood (SpO2), and (2) the percentages of total hemoglobin concentration (SpHb) and blood levels of hemoglobin derivates (co-oximetry) such as methemoglobin (blood with oxidized hemoglobin, SpMet), carboxyhemoglobin (blood with carbon monoxide content, SpCO). In vitro oximeters/cooximeters measure blood samples as laboratory analyzers; pulse oximeters and monitoring instruments make in vivo measurements by determining the light absorbance changes resulting from arterial blood flow pulsations.
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