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  • Molecular assay reagents intended to identify mutations in the cytochrome P450 family 2 subfamily C member 19 (CYP2C19) gene, located at chromosome 10q24, which encodes the protein cytochrome P450 2C19. The protein encoded by this gene is involved in drug metabolism and genetic variants at this locus have been associated with altered response to various drugs including amitriptyline, citalopram, clopidogrel, doxepin, escitalopram, esomeprazole, serotonin reuptake inhibitors, sertraline, and trimipramine.
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